The association of proteins with materials is the core of multiple devices and technologies we use in the diagnostic, biomedical, or energy field. Fascinated by how the interaction with surfaces affects or even enhances the bioactivity of proteins, organic and inorganic materials have been combined with proteins and enzymes to confer novel biosensing, antimicrobial, catalytic, fluorescent, or structural features. Optimising immobilization strategies based on bioaffinity, on chemical crosslinking, or on the physico-chemical properties of the proteins themselves, nanocellulosic materials, metal oxide particles, polymeric microparticles, or polymeric surfaces have been functionalized and often showed an enhanced bioactivity.
Future work will investigate the underlying protein features at the basis of this phenomenon and how this knowledge can be applied to the design of novel biofunctional materials and devices. (see PUBLICATIONS).
You can contact me at greta.faccio(at)gmail.com for questions or collaborations.
NEW: Enhanced biocidal activity and structural transitions of a nanocellulose-nisin biocomposite suspension, accepted at ACS Applied Materials & Interfaces, 16.05.2018
Near-surface structure of plasma polymer films affects surface behavior in water and its interaction with proteins, Accepted by Plasma Chemistry and Plasma Processing,