I have been working for years in academic research and became familiar with scientific topics as different as wheat dough and nanoparticles, kinetics and fluorescence, blood analysis and algal proteins. I am now active in communication, innovation, and innovation protection in the private sector.
My scientific expertise are proteins and enzymes. Proteins an enzymes are at the core of multiple technologies and products we use everyday from the food, to the biomedical, to the energy sector.
I now act as a freelance scientist. I publish articles to communicate scientific topics dealing with protein behaviour or cosmetics. I support scientists in their research and publication, while helping international funding agencies by evaluating proposals. I also consult with start-ups and small companies. I am registered in the Participant Register for EU projects (PIC number 896398244).
38. Faccio G, 2020 Plant complexity and cosmetic innovation, iScience, DOI:https://doi.org/10.1016/j.isci.2020.101358 37. Weishaupt R, Zünd JN, Heuberger L, Zuber F, Faccio G. Robotti F, Ferrari A, Fortunato G, Ren Q, Maniura-Weber K, Guex AG. 2020 Antibacterial, Cytocompatible, Sustainably Sourced: Cellulose Membranes with Bifunctional Peptides for Advanced Wound Dressings, Advanced Healthcare Materials, 1901850. https://doi.org/10.1002/adhm.201901850201936. Faccio* G, Cont A, Mailand E, Zare-Eelanjegh E, Malini RI, Maniura-Weber K, Rossi RM, Spano* F, 2019 Complete inclusion of bioactive molecules and particles in polydimethylsiloxane: a straightforward process under mild conditions, Scientific reports 9 (1), 1-82018
35. Weishaupt R, Heuberger L, Siqueira G, Gutt B, Zimmermann T, Maniura-Weber K, Salentinig S*, Faccio G* Enhanced biocidal activity and structural transitions of a nanocellulose-nisin biocomposite suspension, ACS Appl. Mater. Interfaces, 10, 23, 20170-20181, http://dx.doi.org/10.1021/acsami.8b04470
34. Vandenbossche M, Gunkel-Grabole G, Car A, Bernard L, Rupper P, Maniura-Weber K, Heuberger M, Faccio G, Hegemann D. Near-surface structure of plasma polymer films affects surface behavior in water and its interaction with proteins, Plasma Chemistry and Plasma Processing, 38(4):851-870, https://doi.org/10.1007/s11090-018-9897-z
33. Faccio G, From Protein Features to Sensing Surfaces. INVITED REVIEW, Sensors,
32. Bernard L, Rupper P, Faccio G, Hegemann D, Scholder O, Heuberger M, Maniura-Weber K, Vandenbossche M 2018 Plasma polymer film designs through the eyes of ToF-SIMS, Biointerphases 13, 03B417 doi: .10.1116/1.501604631.Nivala O, Faccio G, Arvas M, Permi P, Buchert J, Kruus K, Mattinene M-L 2017 Characterization of sulfhydryl oxidase from Aspergillus tubingensis, BMC Biochemistry 18:15, doi: 10.1186/s12858-017-0090-4
30. Faccio* G, Salentinig* S. 2017 Enzyme-triggered dissociation of a FRET-based protein biosensor monitored by synchrotron SAXSBiophysical Journal, 113(8):1rg/10.1016/j.bpj.2017.08.044
29. Ihssen J, Jankowska D, Ramsauer T, Reiss R, Luchsinger R, WiesliL, Schubert M, Thöny-Meyer L, Faccio* G 2017 Engineered Bacillus pumilus laccase-like multi-copper oxidase for enhanced oxidation of the lignin model compound guaiacol Protein Engineering, Design & Selection, 1-5. doi: https://doi.org/10.1093/protein/gzx026
28. Weishaupt R, Siqueira G, Schubert M, Kämpf MM, Zimmermann T, Maniura-Weber K, Faccio* G 2017 A Protein-nanocellulose paper for sensing copper ions at the nano- to micromolar level, Adv. Funct. Mat., 27(4), 1604291 doi: 10.1002/adfm.201604291
27. Jankowska D, Bannwarth MB, Schulenburg C, Faccio G, Maniura-Weber K, Rossi RM, Scherer L, Richter M, Boesel L 2017 Simultaneous detection of pH value and glucose concentrations for wound monitoring, Biosensors and Bioelectronics, 87,312–319 http://dx.doi.org/10.1016/j.bios.2016.08.072201626. Vandenbossche* M, Bernard L, Rupper P, Maniura-Weber K, Heuberger M, Faccio G, Hegemann D, Micro-patterned plasma polymer films for bio-sensing, Materials & Design, 114: 123-128. http://dx.doi.org/10.1016/j.matdes.2016.10.058
25. Zare-Eelanjegh E, Bora D, Rupper P, Schrantz K, Thöny-Meyer L, Maniura-Weber K, Richter M, Faccio* G, 2016 Affinity-driven immobilization of proteins to hematite nanoparticles, ACS Appl. Mater. Interfaces, 8 (31), pp 20432–20439 doi 10.1021/acsami.6b03284
24. Faccio* G†, Schulenburg C†, Jankowska D, Richter* M, 2016, A FRET-based biosensor for the detection of neutrophil elastase, Analyst, 2016,141, 1645-1648
DOI: 10.1039/C5AN01747E, Communication
23. Faccio* G, Bannwarth MB, Schulenburg C, Steffen V, Jankowska D, Pohl M, Rossi RM, Maniura-Weber K, Boesel L, Richter* M, 2016, Encapsulation of FRET-based glucose and maltose biosensors to develop functionalized silica nanoparticles, Analyst, 2016,141, 3982-3984, DOI: 10.1039/C5AN02573G, Communication22. Weishaupt R, Siqueira G, Schubert M, Tingaut P, Maniura-Weber K, Zimmermann T, Thöny-Meyer L, Faccio G*, Ihssen J 2015 TEMPO-oxidized nanofibrillated cellulose as a high density carrier for bioactive molecules, Biomacromolecules, 16, 3640−3650, DOI: 10.1021/acs.biomac.5b01100
21. Richter M*, Schulenburg C, Jankowska D, Heck T, Faccio G, 2015, Novel materials
through Nature’s catalysts, Materials Today, 18(8):459-467.
20. Faccio* G, Senkalla S, Thöny-Meyer L, Richter M 2015 Enzymatic multi-functionalization of microparticles under aqueous neutral conditions, RSC Advances, 2015,5, 22319-22325, doi:10.1039/C5RA00669D
19. Faccio G, Schrantz K, Ihssen J, Boudoire F, Hu Y, Mun BS, Bora DK, Thöny-Meyer L, Braun* A, 2015, Charge transfer between photosynthetic proteins and hematite in bio-hybrid photoelectrodes for solar water splitting cells, Nano Convergence , 2:9 doi:10.1186/s40580-014-0040-4201718. Braun* A, Boudoire F, Bora DK, Faccio G, Hu Y, Kroll A, Mun BS, Wilson ST, Biological Components and Bioelectronic Interfaces of Water Splitting Photoelectrodes for Solar Hydrogen Production, Chemistry – A European Journal, Chem. Eur. J. 2014, 20:1–13, doi: 10.1002/chem.201405123
17. Faccio* G, Kàmpf MM, Piatti C, Thöny-Meyer L, Richter* M 2014 Tyrosinase-catalyzed site-specific immobilization of C-phycocyanin to surface, Scientific Reports 4, Article nr.: 5370, doi:10.1038/srep05370
16. Reiss R, Faccio G, Thöny-Meyer L, Richter* M 2014 Cloning, expression and biochemical characterization of the cholesterol oxidase CgChoA from Chryseobacterium gleum, BMC Biotechnology,14:46 doi:10.1186/1472-6750-14-46
15. Ihssen* J, Braun A, Faccio G, Gajda-Schrantz K, Thöny-Meyer L 2014 Light harvesting proteins for solar fuel generation in bioengineered photoelectrochemical cells, Current Protein & Peptide Science, Special Issue, 15(4):374-384. doi: 10.2174/138920371566614032710553014. Nivala O, Mattinen* M-L, Faccio G, Buchert J, Kruus K. 2013 Discovery of novel secreted fungal sulfhydryl oxidases with a plate test screen, Applied Microbiology and Biotechnology,97(21):9429-37 doi: 10.1007/s00253-012-4753-9
13. Faccio* G, Arvas M, Thöny-Meyer L, Saloheimo M. 2013 Experimental and bioinformatic investigation of the proteolytic degradation of the C-terminal domain of a fungal tyrosinase, Journal of Inorganic Biochemistry, 121:37–45, doi:10.1016/j.jinorgbio.2012.12.00612. Heck T, Faccio G, Richter M, Thöny-Meyer *L. 2012 Enzyme-catalyzed protein crosslinking MINI-REVIEW, Applied Microbiology and Biotechnology, 97(2):461-475, doi:10.1007/s00253-012-4569-z11. Faccio G, Kruus K, Saloheimo M, Thöny-Meyer* L. 2012 Bacterial tyrosinases and their applications REVIEW, Process Biochemistry, 47(12):1749–1760, doi: /10.1016/j.procbio.2012.08.01810. Kalliola AK, Savolainen A, Ohra-Aho T, Faccio G & Tamminen T. 2012 Reducing the content of VOCs of softwood kraft lignins for material applications, BioResources, 7(3): 2871-28829. Faccio* G, Flander L, Buchert J, Saloheimo M & Nordlund E. 2012 Sulfhydryl oxidase enhances the effects of ascorbic acid in wheat dough, Journal of Cereal Science, 5(1):37-43, doi:10.1016/j.jcs.2011.10.0028. Faccio* G, Nivala O, Kruus K, Buchert J & Saloheimo M. 2011 Sulfhydryl oxidases: sources, properties, production and applications INVITED MINI-REVIEW, Applied Microbiology and Biotechnology, 91(4):957-66 doi:10.1007/s00253-011-3440-y
7. Faccio G. 2011 Discovery of oxidative enzymes for food engineering. Tyrosinase and sulfhydryl oxidase (Academic dissertation), Espoo 2011. VTT Publications 763. 101 p. + app. 67 p.ISBN 978-951-38-7737-8
6. Faccio* G, Kruus K, Buchert J & Saloheimo M. 2011 Production and characterisation of AoSOX2 from Aspergillus oryzae, a novel flavin-dependent sulfhydryl oxidase with good pH and temperature stability, Applied Microbiology and Biotechnology, 90(3):941-949, doi:10.1007/s00253-011-3129-2
5. Monogioudi* E, Faccio G, Lille M, Poutanen K, Buchert J. & Mattinen M. 2011, Effect of enzymatic cross-linking of β-casein on proteolysis by pepsin, Food Hydrocolloids, 25(1):71-81, doi:10.1016/j.foodhyd.2010.05.0074. Faccio* G, Kruus K, Buchert J & Saloheimo M. 2010, Secreted fungal sulfhydryl oxidases: sequence analysis and characterisation of a representative flavin-dependent enzyme from Aspergillus oryzae, BMC Biochemistry, 11(31), doi:10.1186/1471-2091-11-31
3. Faccio* G, Kruus K, Buchert J & Saloheimo M. 2010, Secreted fungal sulfhydryl oxidases: sequence analysis and characterisation of a representative flavin-dependent enzyme from Aspergillus oryzae, Young Scientist Forum. FEBS Journal, 277:273–305, doi: 10.1111/j.1742-4658.2010.07681.x
2. Faccio* G, Gasparetti* C,Arvas M., Buchert J, Saloheimo M & Kruus K. 2010, Discovery of a new tyrosinase-like enzyme family lacking a C-terminally processed domain: production and characterization of an Aspergillus oryzae catechol oxidase, Applied Microbiology and Biotechnology, 86(1):212-226, doi: 10.1007/s00253-009-2258-3
1. Buchert* J, ErciliCura D, Ma H, Gasparetti C, Monogioudi E, Faccio G, Mattinen M, Boer H, Partanen R, Selinheimo E, Lantto R & Kruus K. 2010, Crosslinking Food Proteins for Improved Functionality, Annual Review of Food Science and Technology, 1(1):112-128. doi:10.1146/annurev.food.080708.100841 Patents 1. Spano F, Faccio G, Rossi R.M. LIQUID DROPLET POLYMER COMPOSITE COMPOSITIONS AND METHODS FOR THEIR PRODUCTION, Oct 2017 (#EP17197227)Book chapters2. Faccio G, 2019 Proteins as Nanosized Components of Biosensors, in Nanomaterials Design for Sensing Applications, 2019, Pages 229-255, Elsevier, Editor: Dr. Olena Zenkina ISBN: 978-0-12-814505-0 Download1. Faccio G, Richter M, Thöny-Meyer L, 2019 Bioprospecting for microbial tyrosinases in Microbial Catalysts. Volume 2, Nova Science Publisher, New York . ISBN: 978-1-53616-088-8 .Download6. Faccio G. Contributor at Medium since Feb 2020
5. Faccio G, 2019, Do your maths, reframe the time spent at work, ThriveGlobal.
4. Faccio G, Cont A, Mailand E, Zare-Eelanjegh E, Innocenti Malini R, Maniura-Weber K, Rossi RM, Spano F, 2019, Complete inclusion of bioactive molecules and particles in polydime-thylsiloxane: a straightforward process under mild conditions, arXiv preprint arXiv:1907.09710
3. Faccio G, 2018 From Protein Features to Sensing Surfaces. Preprints 2018, 2018030012 (doi: 10.20944/preprints201803.0012.v1). INVITED REVIEW submitted to Sensors 02.2018, doi: 10.20944/preprints201803.0012.v1
2. Faccio G, 2017 Sexism: Flagging gender bias doesn’t always work, Nature 547, 32, Correspondence, doi:10.1038/547032c
1. Faccio G, Swiss fight drug-resistant bacteria on many fronts, 20.07.2016Publications where my contribution is acknowledged
1. Wang CS, Stewart RJ. The multipart copolyelectrolyte adhesive of the sandcastle worm, Phragmatopoma Californica (Fewkes): catechol oxidase catalyzed curing through peptidyl-DOPA, Biomacromolecules, 14 (5), pp 1607–1617 2012, doi: 10.1021/bm400251k
2. Caldinelli L, Pedotti M, Motteran L, Molla G, Pollegioni L. FAD binding in glycine oxidase from Bacillus subtilis, Biochimie, 91(11–12):1499–1508Empa-Forscher entwickeln Wundverband, der Bakterien abtötet“, Tagblat (file)“Ein Wundverband, der Bakterien abtötet”, Empa weibsite (file)hat a privilege to be interviewed by Elizabeth for the project at With a Science Degree – Interviews to help you better understand your career options. @aScienceDegree!SciLight – Time-of-flight spectrometry of biointerfaces helps link deposition mechanisms to surface design, 05.04.2018 PDF: 18 _pdf_archive_SCILYT_vol_2018_iss_14_140007_1in Papier, das Kupfer aufspürt, Biosensor für Schwermetalle entwickelt,Analytica World, 06.10.2017 PDF: 2017 Analytica World Cover Advanced Functional Materials – A Protein-Nanocellulose Paper for Sensing Copper Ions at the Nano- to Micromolar Level Thematic Platform in vitro Diagnostics Technological Progress with a Powerful Network (PDF: 2016-chimia-platform_invitrodiagnostics) Encapsulation of FRET-based glucose and maltose biosensors to develop functionalized silica nanoparticles the gamut of cultures colors the everyday life of Pro-Enz Project A bit shy Chinese man and four exotic beauties from southernEurope, where women are told to be dark and passionate.Finlandas a milieu and one of the most appreciated pioneers of science, Marie Curie, on the background. All this gets combined in the Pro-Enz project that aims to find new cross-linking enzymes for tailoring protein interactions and functionalities in food matrix. The fulcrums of the project are Hairan Ma fromChina, Dilek Ercili fromTurkey, Evanthia Monogioudi fromGreeceand Greta Faccio and Chiara Gasparetti fromItaly. Each of these Marie Curie-researchers is going spend at VTT in Espoo three years to obtain study credits for the PhD and to get work experience in the field of science during the time. Above-mentioned mixture of cultures sounds a bit explosive. Has the door of laboratory got slammed? “Not at all”, convince the researchers. On the contrary, they are good friends at work and on the free time alike. “People are different. Someone could think that this bottle of water doesn’t taste good at all, even though I like it. I can understand the point of view without having to change my own opinion”, demonstrates Evanthia the successful co-operation with her bottle of water. Different cultural backgrounds are often amusing tonic of the day. Some comments of Hairan give perspective on the population ofChina: “Hairan might say that the city is small. There are only two million inhabitants”, wonder women smiling. Hairan was at first amazed by women’s naturally curly hair. For him it was hard to believe that the hair can be curly without the help of hairdresser. To Finland and to VTT the young researchers were mainly drawn by interesting-sounded EU-project and challenging work. A better salary and opportunities for independent living were also seeing tempting. Cupid had made his tricks as well: one of the researchers came toFinlandnot only because of an interesting job, but also because of her Finnish boyfriend. This leads the conversation to different direction: how to combine relationships and work? According to women, employers’ attitudes toward relationships are more positive inFinlandthan they are in their home countries. This is surprising because you could think that in the countries, where close family relations are so important, also relationships would be appreciated. “In southernEuropethey think that you can’t combine family and work effectively. They think that family takes time and efficiency from the work,” women explain. According to researchers, working at VTT has been a positive experience: “As in Finland in general, also at VTT everything is well organized and working is therefore easy. You get help when ever you need it and everyone is smiling at you even though you don’t know them. The technicians are very professional and they know what they are doing.” The researchers can’t tell any negative points off-hand. After a while Greta admits that sometimes things are a bit too authorized. Despite that the researchers are mainly glad at their work. Working at project pleases them too: “In the project the most interesting thing are the different points of view. You can’t get complete solutions to your problems. Instead each one can only help only in the field of their expertise. These little crumbs of knowledge form the answer to your problem.”